Project Description
OxyLite & OxyLitePro
제품 소개
OxyLite는 조직 내 pO2와 산소분압 정보를 저산소 상태에서도 민감하고 정확하게 측정하는 산소분압 모니터링 장비입니다.
calibration, sensor drift, 전용 PC나 소프트웨어가 필요 없어, 사용이 매우 간단한 dissolved oxygen monitor 입니다.
형광 기반의 기술을 이용한 oxygen monitoring을 통해 mmHg or kPa 당 용존산소량을 정확하게 측정할 수 있습니다.
생체 내에서, 혈액의 헤모글로빈 산소 상태를 나타내는 oxygen saturation assessment (pulse oximetry)와 달리 세포 및 조직에 산소 가용성을 직접 판독할 수 있습니다.
3세대 opto-electronics를 사용하여 저산소 상태(0~15 mmHg)에서 pO2 range 정보를 민감하고 정확하게 제공합니다.
* 현재 oxylite와 센서는 인간 실험체에 사용할 수 있는 CE 또는 FDA 규정 승인을 받지 않았습니다.
* 그러므로 의료/진단용으로 사용 할 수 없으며 연구용으로만 사용되어야 합니다.
제품 특징
• 측정 시점에서 산소의 소비가 0이기 때문에 극도의 저 산소 상태에서도 지속적이고 절대적인 산소 감지에 적합합니다.
• EEPROM 기술이 내장되어 있어 모든 보정 절차를 생략하여 탁월한 사용 편의성을 제공합니다.
• In vivo pO2 측정과 in vitro(hypoxic cell culture, tissue constructs)의 용존 산소량 측정 모두 완벽하게 지원합니다.
• 산소 센서의 직경은 대략 230 – 750µm 로 tissue monitoring에 적합하며, 사용시 조직 손상을 최소화합니다
Single-channel monitor
– Oxygen (pO2) & temperature monitor
– In vivo & in vitro applications
– No calibration procedures
Multi-channel monitor
– Oxygen (pO2) & temperature monitor
– In vivo & in vitro applications
– No calibration procedures
Data Examples (LabChart pro 화면)
A model of muscle fatigue in mice. 이 값은 mmHg/ degrees C 로 보여집니다.
Supplied in sealed Tyvek® pouches
재사용 가능한 다양한 종류의 oxygen sensors는 안전한 보관을 위해 전용 파우치에 제공됩니다.
연구 및 실험 분야
• 생리학/허혈 연구: 조직의 산소 공급 부족으로 인한 변화를 연구합니다.
• 종양/암 연구: 종양 혈관 생성 과정과 산소 수준을 모니터링합니다.
• 시험관 내 실험: 세포 배양 및 조직 구성체의 용존 산소량을 측정합니다.
• 안과학: 안구 조직의 산소 수준을 연구합니다.
• 성형외과/상처 치유 연구: 조직 및 상처의 산화 과정을 연구합니다.
• 장기/쇼크 연구: 장기 이식 중 또는 쇼크 상태에서 생체 장기의 산소 수준을 모니터링합니다.
• 뇌/뇌졸중/MCAO 연구: 뇌졸중 모델에서 대뇌 산소량을 측정하고 뇌와 척수 손상에서 산소의 중요성을 연구합니다.
Applications
• Physiology/Ischaemia
• Methodology/Validation
• Tumour/Cancer
• In Vitro Applications
• Ophthalmology
• Plastic Surgery/Wound Healing
• Vital Organs/Shock
• Cerebral/Stroke/MCAO
제품사양
| GENERAL | |
| Dimensions | OxyLite: 95mm (H) x 290mm (W) x 260mm (D) OxyLite Pro: 150mm (H) x 310mm (W) x 280mm (D) |
| Weight | OxyLite: 2kg / 4.5lbs OxyLite Pro: 4kg / 9lbs |
| Operating temperature | 10 – 30°C |
| Operating humidity | 0 – 70% (non-condensing) |
| Power requirements | OxyLite: VAC 100-240V, 50-60Hz, 30W max OxyLite Pro: External PSU (100-240V / 47-63 Hz), 40W max |
| Fuse rating | OxyLite: 2 x T1.6A OxyLite Pro: Not applicable |
| Number of sensors supported / Number of channels |
OxyLite: 1 OxyLite Pro: 2 OxyLite Pro XL: 4 |
| Display | OxyLite: 40 character alphanumeric OLED OxyLite Pro: High contrast 800 x 480 LCD touch-screen |
| Instrument configuration | OxyLite: Via function button at rear OxyLite Pro: Via touch-screen display |
| Analogue voltage outputs | OxyLite: 2 x male BNC connectors (2 outputs) OxyLite Pro: 1 x 15-pin D-type (4 outputs) OxyLite Pro XL: 2 x 15-pin D-type (8 outputs) |
| LED excitation wavelength | 525nm |
| Luminescence wavelength | 650nm |
| Digital output | USB type B interface for data recording to LabChart software (PC only) |
| Analogue output | OxyLite: 2 x BNC connectors for data recording (0-5V) OxyLite Pro: 15-pin D-connector interface for data recording via BNC adapter cable (0-5V) |
| PERFORMANCE | |
| Mode of operation | Luminescence decay lifetime (pO2) / T-type thermocouple or manual user input (temperature) |
| Measurement units (displayed) | mmHg or kPa / ºC |
| Measurement range | 0~200mmHg; 0~26.6kPa / 0~50ºC |
| Measurement resolution | 0.1mmHg / 0.1ºC |
| Measurement accuracy | Oxygen: ±0.7mmHg (0~7mmHg) ±10% of reading (7~150mmHg) ±15% of reading (150~200mmHg)Temp: ±0.2ºC |
| Measurement response time | < 20s (standard oxygen sensor) / < 2s (temperature) |
| Measurement sampling rate | 1Hz (user definable on OxyLite Pro models) |
| Measurement acquisition time | 1s |
| Measurement averaging | 5s, rolling |
| Display update interval (numerical) | 2s (5s rolling averaged) |
| Validated temp compensation range | 10ºC~45ºC |
| Sensor identification | Automatic; integrated connector EEPROM |
| Sensor calibration | Factory pre-calibration (unique per sensor); valid 6 months |
| Sensor shelf-life | 2 years from factory calibration (used or unused) |
| Sensor longevity | 48 hours accumulated usage at default sampling rate |
| Analogue data output range | 0~5V (0~200mmHg / 0~50ºC) (default) |
| Analogue data output rate | 1Hz |
Oxygen sensors for OxyLite™ and OxyLite™ Pro
Bare-Fibre Oxygen Sensors
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NX-BF/O/E – Oxygen-only bare-fibre sensor Suitable for localized oxygen measurements from virtually any tissue type, or for in vitro dissolved oxygen applications. |
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NX-BF/OT/E – Oxygen/Temperature bare-fibre sensor Suitable for localized combined oxygen/temperature measurements from virtually any tissue type, or for in vitro dissolved oxygen applications. |
Needle Oxygen Sensors
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NX-NP/O/E – Oxygen-only needle-encased sensor Suitable for localized oxygen measurements from virtually any tissue type, or for in vitro dissolved oxygen applications. |
Large Area Oxygen Sensors
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NX-LAS-1/O/E – Oxygen-only large area sensor (1 mm²) Suitable for localized oxygen measurements from virtually any tissue type, or for in vitro dissolved oxygen applications. |
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NX-LAS-1/OT/E -Oxygen/Temperature large area sensor (1 mm²). Suitable for localized oxygen measurements from virtually any tissue type, or for in vitro dissolved oxygen applications. |
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NX-LAS-8/O/E –Oxygen-only large area sensor (8 mm²) Suitable for very large tissue sampling area/volume (8 mm²) for area-averaged tissue oxygen/temperature measurements. |
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NX-LAS-8/OT/E – Oxygen/Temperature large area sensor (8 mm²) Suitable for very large tissue sampling area/volume (8 mm²) for area-averaged tissue oxygen/temperature measurements. |
Implantable oxygen sensor-NX-CI ADAPTER required
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NX-CI/BF/O/E – Implantable bare-fibre type oxygen sensor Suitable for chronic tissue implantation. |
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NX-CI/LAS-1/O/E – Implantable large area type oxygen sensor (1 mm²) Suitable for 1 mm² tissue sampling area/volume. |
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NX-CI/LAS-8/O/E – Implantable large area type oxygen sensor (8 mm²) Suitable for very large tissue sampling area/volume (8 mm²) for area-averaged tissue oxygen measurements. |
Optional Accessory
OxyData™ software
OxyLite™ 및 OxyFlo™ 모니터에서 생성된 산소, 온도 및/또는 혈류 측정값을 PC에 지속적으로 기록할 수 있도록 지원합니다.
PowerLab 4/26 데이터 저장 장치
Economically priced 4 channel data acquisition featuring 4 analog inputs.
LabChart® Pro
PowerLab® module에 사용하는 전용 소프트웨어로 본체 후면의 USB 출력을 통해 실시간 측정치를 PC로 direct streaming 할 수 있습니다.
NX-CI ADAPTER
전문 이식형 (‘CI’ type) 산소 센서는 이 2.5m 연결 어댑터가 필요합니다.
Journal Citations
Comprehensive PDF record of publications citing our oxygen monitors (May 2024) -584kb
Articles of note
Monitoring oxygen in the eye
by Justin Croft, August 2024
Chronically implantable sensors: going beyond acute tissue oxygen monitoring
by Justin Croft, June 2024
Phantom Models and the Importance of Dissolved Oxygen Measurements
by Justin Croft, January 2024
The importance of oxygen in tumours; accelerating oncology research
by Justin Croft, June 2023
Utilizing cerebral oxygen and blood flow to provide insights into brain function, damage, and recovery in vivo
by Justin Croft, November 2022
Oxygen and the Biocompatibility of Scaffolds in Tissue Engineering
by Justin Croft, February 2022
A scientific review of oxygen and its effect in ageing
by Justin Croft, June 2021
A scientific review of oxygen and its effects in bone and osteo-biology
by Justin Croft, August 2021
Some recent citations of note:
Vogiatjis J, Noe KM, Don A, Cochrane AD, Zhu MZL, Smith JA, Ngo JP, Martin A, Thrift AG, Bellomo R, Evans RG (2022). Association between changes in norepinephrine infusion rate and urinary oxygen tension after cardiac surgery. J Cardiothorac Vasc Anesth
Kazmi S, Khan MA, Shamma T, Altuhami A, Ahmed HA, Mohammed Assiri A, Broering DC (2022). Targeting Interleukin-10 Restores Graft Microvascular Supply and Airway Epithelium in Rejecting Allografts. Int J Mol Sci
Wang CH, Huang CH, Tsai MS, Wang CC, Chang WT, Liu SH, Chen WJ (2022). Inhaled Carbon Dioxide Improves Neurological Outcomes by Downregulating Hippocampal Autophagy and Apoptosis in an Asphyxia-Induced Cardiac Arrest and Resuscitation Rat Model. J Am Heart Assoc
Malik H, Wolff MD, Teskey GC, Mychasiuk R (2022). Electrographic seizures and brain hyperoxia may be key etiological factors for postconcussive deficits. J Neurophysiol
Konieczny P, Xing Y, Sidhu I, Subudhi I, Mansfield KP, Hsieh B, Biancur DE, Larsen SB, Cammer M, Li D, Landén NX, Loomis C, Heguy A, Tikhonova AN, Tsirigos A, Naik S (2022). Interleukin-17 governs hypoxic adaptation of injured epithelium. Science
주문정보
| 제품번호 | 품명 | 규격 | 제조사 | 비고 |
| OXYLITE | OXYLITE 1 Channel tissue pO2 and temperature monitor |
set | Oxford Optronix | Body only |
| OXYLITE PRO | OXYLITE PRO 2 Channel tissue pO2 and temperature monitor with touch screen |
set | Oxford Optronix | Body only |
| OXYLITE PRO XL | OXYLITE PRO XL 4 Channel tissue pO2 and temperature monitor with touch screen |
set | Oxford Optronix | Body only |
| Oxygen Sensors, 최소 주문량-2개 | ||||
| NX-BF/O/E | pO2 ‘Bare-Fibre’ sensor | ea | Oxford Optronix | |
| NX-BF/OT/E | pO2/Temp ‘Bare-Fibre’ sensor | ea | Oxford Optronix | |
| NX-BF/OF/E | pO2/Flow ‘Bare-Fibre’ sensor | ea | Oxford Optronix | |
| NX-BF/OFT/E | pO2/Flow/Temp ‘Bare-Fibre’ sensor | ea | Oxford Optronix | |
| NX-NP/O/E | pO2 Needle sensor (23G) | ea | Oxford Optronix | |
| NX-LAS-1/O/E | pO2 Large Area Sensor (3 m length; 1 mm2 sampling area) | ea | Oxford Optronix | |
| NX-LAS-1/OT/E | pO2/Temp Large Area Sensor (3 m length; 1 mm2 sampling area) | ea | Oxford Optronix | |
| NX-LAS-8/O/E | pO2 Large Area Sensor (3 m length; 8 mm2 sampling area) | ea | Oxford Optronix | |
| NX-LAS-8/OT/E | pO2/Temp Large Area Sensor (3 m length; 8 mm2 sampling area) | ea | Oxford Optronix | |
| NX-CI/BF/O/E | Implantable bare-fibre type oxygen sensor | ea | Oxford Optronix | NX-CI ADAPTER required |
| NX-CI/LAS-1/O/E | Implantable large area type oxygen sensor (1 mm²) | ea | Oxford Optronix | NX-CI ADAPTER required |
| NX-CI/LAS-8/O/E | Implantable large area type oxygen sensor (8 mm²) | ea | Oxford Optronix | NX-CI ADAPTER required |
| Data Acquisition / Recording – 데이터 저장 장치 옵션 | ||||
| OxyData™ software |
Data acquisition software for OxyLite™ and OxyFlo™ monitors | software | Oxford Optronix | |
| POWERLAB 4/26 | 4 Channel data recorder (PC/Mac), incl. LabChart® software, 5 years free updates |
unit | ADInstruments | |
| POWERLAB 8/35 | 8 Channel data recorder (PC/Mac), incl. LabChart® software, 5 years free updates |
unit | ADInstruments | |
| POWERLAB 16/35 | 16 Channel data recorder (PC/Mac), incl. LabChart® software, 5 years free updates |
unit | ADInstruments | |
| LabChartpro | LabChart® Pro acquisition software (PC/Windows® only), incl. 1 user license, 5 years free updates, USB cable(s) |
software | ADInstruments | |
| Accessories | ||||
| NX-CI ADAPTER | Connecting adapter for implantable pO2 sensors (2.5 m) | ea | Oxford Optronix | |
| OLO-BNC | BNC data cables for OxyLite or OxyFlo. Pack of 2 (1 m) | ea | Oxford Optronix | |
| NX-BNC | High-density 15-pin D-connector to 4 BNC data adapter cable for OxyLite Pro or OxyFlo Pro (1 m) | ea | Oxford Optronix | |
Document
| 제품 자료 | BioD_Flyer_EN_OxyLite & OxyLitePro.pdf | Upload date: 2025.11.11 |
| BioD_Manual_EN_OxyLite.pdf | Upload date: 2025.11.11 | |
| BioD_Manual_EN_OxyLitePro.pdf | Upload date: 2025.11.11 |