Molnova Natural Compounds

제품 소개

Molnova는 화학 및 생물학 연구 제품 및 서비스를 전문으로 하는 글로벌 생명 공학 기업입니다.
20개 이상의 signaling pathways와 400여개의 표적에서 9,000개 이상의 제품을 제공하는 글로벌 화합물 및 펩타이드 공급업체 중 하나 입니다.
Molnova는 암, 감염, 면역학, 신경과학, 세포 사멸 및 대사 장애 등과 같은 다양한 연구 분야에 걸쳐 광범위한 제품 라인을 보유하고 있습니다.

Molnova는 새로운 생명 과학 시약, inhibitors, peptides, activator, API 및 과학적 용도의 natural compound를 포함하여 광범위한 고품질의 연구용 chemical compound를 제공합니다.
또한 chemical synthesis, peptide synthesis, drug screening 등의 최신 맞춤형 서비스를 제공합니다.
Molnova는 pre-clinical drug의 연구를 위한 신규 표적 및 신규 후보 화합물에 중점을 두고 있으며, 매년 1,000개 이상의 신제품을 출시하고 있습니다.

Hot Targets

Akt	Aurora	Bcl-2	Bcr-Abl
c-Myc	COX	DAG	DPP-4
HDAC	Hedgehog	HER2	HIF
JAK	JNK	LTR	MAPK
p38 MAPK	p53	PARP	PD-1/PD-L1
PKA	PKC	PLK	PTEN
Src	STAT	TGF-beta	Smad
BTK	CaMK	cAMP	c-Met
EGFR	ERK	FLT3	GSK-3
HSP	IAP	IGFR	IL Receptor
MEK	mTOR	NF-κB	OX Receptor
PDGFR	PDK	PERK	PI3K
Raf	Rho	ROCK	ROS
TNF-alpha	Tyrosinase	VEGFR	More…

Research Areas

Cancer

Blood cancer(217)	Bone Cancer(12)	Brain Cancer(27)	Breast Cancer(73)
Chemotherapeutic(44)	Colon Cancer(21)	Gastric Cancer(17)	Kidney Cancer(15)
Liver Cancer(24)	Lung Cancer(77)	Ovarian Cancer(27)	Pancreatic Cancer(18)
Prostate Cancer(21)	Skin Cancer(17)	Solid Tumors(77)	Thyroid Cancer(1)

Cardiovascular Disease

	Dyslipidemia(25)	Atherosclerosis(10)	Coagulation Disorder(1)	Heart Arrhythmia(25)
	Hypercholesterolemia(9)	Hypertension(56)	Ischemia(5)	Thrombosis(38)

Inflammation/Immunology

	Rheumatoid Arthritis(53)	Allergy(17)	Asthma(47)	COPD(34)
	Dermatitis(6)	Gout(1)	Multiple Sclerosis(21)	Psoriasis(22)

Infection

Rhinovirus Infection(3)	Bacterial Infection(51)	CMV Infection(4)	Ebola Virus Infection(3)
Fungal Infection(14)	HBV Infection(7)	HCV Infection(48)	HIV Infection(52)
HPV Infection(2)	HSV Infection(8)	Influenza(10)	Parasite Infection(21)

Products

Wnt/Notch/Hedgehog

Autotaxin	Axin	Beta-catenin
γ-secretase	Dishevelled	Dkk-1
Frizzled	Gli	Hippo
Notch	Porcupine	Smoothened (Smo)
STAT	TNIK	Wnt/beta/catenin

Tyrosine Kinase

FLT3	Ack1 (TNK2)	Angiopoietin Receptor
Bcr-Abl	BMX Kinase	Breast Tumor Kinase
BTK	c-Fes Kinase	c-RET
CSF1R	DDR	Ephrin Receptor
FAK	Insulin Receptor\	Src
TAM Receptor	Tie-2	Trk Receptor

TGF-beta/Smad

TGFBR

–

Proteasome/Ubiquitin

Proteasome	Caspase	Cysteine Protease
DUB	E1	E2
E3 Ubiquitin Ligase	Endogenous Metabolite	HSP
NEDD8	Other Targets	p97
Serine Protease	Tyrosinase

PROTACs

E3 Ligase Ligand

PEGn

PROTAC

PI3K/Akt/mTOR signaling

PDK	Akt	S6 Kinase
GSK-3	MELK	mTOR
PI3K	PI4K	PIKfyve

Others

14-3-3 Protein	AAK1	Amyloids
Antioxidant	BMI-1	ChoK
Clathrin	DGK	Fluorescent Dye
Glutathione Reductase	GRK (GPCRK)	mPTP
Other Targets	PCSK9	Platelet aggregation
PTEN	SMN2	Spliceosome
Thrombin	TSPO	VD

Nuclear Receptor/Transcription Factor

c-Fos/AP-1	CREB/CBP	eIF
Foxo1	GATA Binding Protein	Keap1-Nrf2
KLF	LXR	MLR
PGC-1α	Progesterone Receptor	RAR/RXR
ROR

NF-κB

MALT1	TAK1	NOD
Free radical scavengers

Neuroscience

Norepinephrine	P2 Receptor	Adiponectin Receptor
Other Targets	Gamma-secretase	GluR
GlyT inhibitor

Natural Products

Flavonoids

Terpenoids

Phenols

Microbiology/Virology

HCV	Antibiotic ribosome	Antifection
Antifungal Arenavirus	CMV	Enterovirus
Filovirus	Fungal	GluCls
HBV	HIV	HPV
HSV	Influenza Virus	Other Targets
Parasite	Reverse Transcriptase	Rhinovirus

Metabolic Enzyme/Protease

CYPs	11β-HSD	15-PGDH
ACC	ACE	AChE
Adenylate Cyclase	ALDH	Aldose Reductase
Aminopeptidase	Transferase	BACE
Casein Kinase	CAT	Cathepsin
CETP	COMT	CPG2
Decarboxylase	Dehydrogenase	DGAT
Dopamine beta-hydroxylase	DPP	Elastase
FAAH	TPH	Factor Xa
Fatty Acid Synthase	Ftase	FXR
Glucokinase	GSNOR	Guanylate Cyclase
HMGCR	IDH	IDO
Xanthine Oxidase (XAO)	IMPDH	LDH
Steroid Sulfatase (STS)	Lipase	Lipid
Lipoxygenase	MAGL	SCD
MAO	Retinoid Receptor	MMP
NAMPT	Neprilysin	NKCC
Other Targets	P450	PAI-1
Vitamin Phosphatase	Renin Phospholipase	PPAR
Protein Phosphatase/PTP	Thioredoxin LDL

Membrane Transporter/Ion Channel

GlyT	AMPK	ASBT Transporter
BCRP	Beta Amyloid	Carbonic Anhydrase
Chloride Channel	CRAC Channel	CRM1
Exportin-1	FABP	GAT
GLUT	Glutamate Transporter	HCN Channel
iGluR	Monoamine Transporter	Monocarboxylate Transporter
MTP	nAChR	NADPH
Na-K-ATPase	NKCC	NMDAR
OCT	Other Targets	P2X Receptor
P-glycoprotein	Proton Pump	Sodium Channel
TRP/TRPV Channel	URAT1

MAPK/ERK Signaling

MEK	p38 MAPK	Ras
Raf	ERK	JNK
MAPKAPK2 (MK2)	MAP4K	MNK
MLK	Other Targets

JAK/STAT Signaling

STAT Pim

–

Immunology/Inflammation

PGE synthase	Amino Acids and Derivatives	Antiviral CD110
Cell wall	Complement System	FLAP
Hydroxylase	Interferon Receptor	IRAK
IκB kinase (IKK)	Lipoxygenase	LTR
MyD88	NOS	PD-1/PD-L1
RLR	ROS	Scavenger Receptor
SphK	STING	TLR

GPCR/G Protein

Urotensin Receptor	ACAT	Angiotensin Receptor
Antibacterial	Bombesin Receptor	Vasopressin Receptor
Bradykinin Receptor	Calcium Channel	cAMP Cannabinoid Receptor
CaSR	CGRP Receptor	Chemokine Receptor
Cholecystokinin Receptor	CRF Receptor	Dopamine Receptor
Endothelin Receptor	FFAR Galanin Receptor	GHSR
Glucagon Receptor	GPCR19	GPR119
Hedgehog (Hh)	Histamine Receptor	Imidazoline Receptor
Leukotriene Receptor	LHR	LPA Receptor
Somatostatin Receptor	Lysophospholipid Receptor	mAChR
MCHR	Melanocortin Receptor	Melatonin Receptor
mGluR	Motilin Receptor	Neurokinin Receptor
Neuropeptide Y Receptor	Neurotensin Receptor	Orexin Receptor
Other Targets	OXTR	P2Y Receptor
PAR	Platelet-activating Factor Receptor	Prostaglandin Receptor
PTH Receptor	S1P Receptor	SGLT

Endocrinology/Hormones

GPR	MRP	GR
Aromatase	Opioid Receptor	Estrogen Receptor/ERR
CaMK Androgen Receptor (AR)	RAAS	THR
COX	Reductase	Adrenergic Receptor
5-HT Receptor	ATPase	Annexin A
AhR AChR

Cytoskeleton/Cell Adhesion Molecules

Akt	Microtubule/Tubulin	Myosin
Selectin	Kinesin	Dynamin
Dynein	Galectin	Cadherin
HSP	Ezrin	Arp2/3 complex
Glucokinase	Arginase	GST
Gap Junction Protein

Chromatin/Epigenetic

Sirtuin	HMTase	DNMT
Histone Demethylase	HAT	Epigenetic Reader Domain
Bromodomain	MicroRNA	CRISPR/Cas9 COX

Cell Cycle/DNA Damage

ABC	AChR	Antifolate
ATM/ATR	Aurora Kinase	CLK
c-Myc	DHFR	DNA Alkylator
DNA gyrase	DNA Repair Protein	DNA/RNA Synthesis
DNA-PK	GPR	HDAC
Hec1/Nek2	Integrin	LIM Kinase (LIMK)
Mps1/TTK	Nucleoside Antimetabolite/Analog	Other Targets
PARP	PLK	Potassium Channel
RAD51	Rho	ROCK
Telomerase	Topoisomerase	Wee1

Autophagy

Mitophagy	Atg	Autophagy
ULK	LRRK2	SIK
WNK Kinase	Sigma receptor	Other Targets
Arginase	CXCR	Thrombin
CCR

Apoptosis

IAP	MDM2-p53	PKA
Fas Receptor	DAPK	IL Receptor
Apoptosis	Caspase	Other Targets
Ferroptosis	PKD	RIP kinase
PERK	Serine/threonin kinase	TNF
Apaf-1	Adenosine Receptor	CFTR NF-κB p53