Project Description
OxyFlo & OxyFloPro
제품 소개
OxyFlo는 3세대 Laser-Doppler 방식의 실시간 조직 혈류 모니터링 장비입니다.
(혈류량을 확인하는 것이 아니라 ‘혈류 흐름의 변화’를 보는 장비입니다.)
급성 실험 모델에서 혈류 변화를 관찰하는 데에 매우 이상적이며, 침습 또는 비침습 조직의 혈류 측정을 위한 다양한 프로브 유형을 지원합니다.
측정치는 0 ~ 9999 BPU (blood perfusion units) 까지 display에 표시됩니다.
별도의 데이터 저장장치와 옵션 소프트웨어인 LabChart® Pro data recording and analysis software 를 사용하면,
모니터의 후면에 있는 전용 USB 출력을 통해 실시간 측정치를 PC로 direct streaming도 가능합니다.
* 현재 oxyflo와 probe는 인간 실험체에 사용할 수 있는 CE 또는 FDA 규정 승인을 받지 않았습니다.
* 그러므로 의료/진단용으로 사용 할 수 없으며 연구용으로만 사용되어야 합니다.
Application
•Blood flow monitoring in peripheral vascular disorder
•Cerebral perfusion monitoring in models of stroke and brain injury
•Tumor perfusion monitoring/angiogenesis
•Blood flow in free flaps and pedicle flaps
•Wound healing
•Gastroenterology
제품 특징
• 3세대 레이저 도플러 조직 혈류 모니터
• 타의 추종을 불허하는 사용 편의성
• 지속적인 실시간 조직내 혈류 측정
• 센서의 움직임으로 인한 Signal artifact 억제
• 최대 4개 위치에서 동시에 측정
• 뛰어난 정확도, 안정성 및 성능
• 직관적인 터치스크린 컨트롤
Single-channel monitoring
-Uncompromised reliability
-Measurements in acute experimental models
Multi-channel monitoring
-Uncompromised reliability
-Enhanced productivity & features
Data Examples ( LabChart® Pro)
A model of Middle Cerebral Artery Occlusion in rat. 이 값은 blood perfusion units (BPU) 로 보여집니다.
Dedicated protective case
재사용 가능한 다양한 종류의 fibre-optic probe는 안전한 보관을 위해 전용 보호 케이스에 제공됩니다.
제품사양
| GENERAL | |
| Dimensions | OxyFlo: 95mm (H) x 290mm (W) x 260mm (D) OxyFlo Pro: 150mm (H) x 310mm (W) x 280mm (D) |
| Weight | OxyLite: 2kg / 4.5lbs OxyLite Pro: 4kg / 9lbs |
| Operating temperature | 10~30°C |
| Operating humidity | 0~70% (non-condensing) |
| Power requirements | OxyFlo: VAC 100-240V, 50-60Hz, 30W max OxyFlo Pro: External PSU (100-240V / 47-63 Hz), 40W max |
| Fuse rating | OxyFlo: 2 x T1.6A OxyFlo Pro: Not applicable |
| Number of sensors supported /Number of channels |
OxyFlo: 1 OxyFlo Pro: 2 OxyFlo Pro XL: 4 |
| Display | OxyFlo: 40 characters alphanumeric OLED OxyFlo Pro: High contrast 800 x 480 LCD touch-screen |
| Instrument configuration | OxyFlo: Via function button at the rear OxyFlo Pro: Via touch-screen display |
| Analogue voltage outputs | OxyFlo: 2 x male BNC connectors (2 outputs) OxyFlo Pro: 1 x 15-pin D-type (4 outputs) OxyFlo Pro XL: 2 x 15-pin D-type (8 outputs) |
| Laser type | Temperature-stabilized semi-conductor laser diode |
| Laser wavelength | 785 ±10nm |
| Laser classification | Class 1 (EN 60825-1:1994, 21 CFR 1040.10 and 1040.11) |
| Laser power | <0.5mW from probe tip/underside |
| Digital output | USB type B interface for data recording to LabChart software (PC only) |
| Analogue output | OxyFlo: 2 x BNC connectors for data recording (0-5V) OxyFlo Pro: 15-pin D-connector interface for data recording via BNC adapter cable (0-5V) |
| PERFORMANCE | |
| Mode of operation | Laser Doppler flowmetry |
| Measurement units (displayed) | 0~9999 BPU (blood perfusion units) |
| Stability of reading | ±5% |
| Sampling rate | 200Hz |
| Measurement averaging | 200ms (Flow); 5ms (Raw); 5s (ART); 200ms (Backscatter), rolling |
| Display update interval (numerical) | 2s (5s rolling averaged) |
| Probe identification | Automatic; monitor stores one-time calibration |
| Probe calibration | Factory or user-calibrated using Oxford Optronix motility standard |
| Probe shelf-life | Unlimited |
| Zeroing | Automatic, controlled |
| Default analogue data output range | 0~5V (=0~5000 BPU or 0~100% Backscatter) |
| Analogue data output rate | 65Hz |
Blood flow probes for OxyFlo and OxyFloPro
Surface Blood Flow Probes
Tissue attachment via double-sided adhesive rings (product code ‘MSP140AR’) or by suture.
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MSP100NX-Standard probe for blood flow from tissue surfaces for measurements of microvascular blood flow on tissue surfaces |
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MSP110NX-Digit probe for blood flow from rounded surfaces for measuring cutaneous blood flow in the digits |
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MSP300NX-Miniature probe for blood flow from tissue surfaces (suturable) for non-invasive tissue surface blood flow monitoring for semi-invasive monitoring of blood flow from muscle and internal organ surfaces |
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MSP310NX-Miniature probe for blood flow from tissue surfaces (non-suturable) for non-invasive tissue surface blood flow monitoring for semi-invasive monitoring of blood flow from muscle and internal organ surfaces |
Needle Blood Flow Probes
Typically positioned using an external clamp
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MNP100NX-Standard needle blood flow probe for invasive blood flow measurements or non-invasive blood flow measurements from tissue surfaces |
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MNP100NX-3/10-Standard needle blood flow probe for MCAO for cerebral microvascular blood flow measurements in MCAO and stroke applications |
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MNP110NX-Fine needle blood flow probe for minimal tissue trauma during invasive insertion for measuring microvascular blood flow within the muscle, tumors, internal organs, and brain tissue |
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MNP150NX-Bent-tip needle blood flow probe for specialist applications such as gingiva and nasal mucosa |
Specialist Blood Flow Probes
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MSF100NX– Single-fibre implantable blood flow probe for chronic implantation, the MSF100NX can be directly inserted into tissue using a standard 22G i.d. cannula * Flow measurements are made by attaching the MSF Driver |
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NX-BF/F-Bare-fibre type blood flow probe for direct insertion into tissue (via catheter or cannula) for measurement of microvascular blood flow from deeper tissue regions. * Tissue placement via introducer (e.g. Angiocath®) |
Optional Accessory
ValueADC 아날로그 데이터 저장장치
The 12-input analog data acquisition module
PowerLab 4/26 디지털 데이터 저장 장치
Economically priced 4 channel data acquisition featuring 4 analog inputs with LabChart® Pro
LabChart® Pro
옵션 소프트웨어인 LabChart® Pro를 사용하면 본체의 후면에 있는 전용 USB 출력을 통해 실시간 측정치를 PC로 direct streaming 가능합니다.
Calibration kit for blood flow probes
프로브을 별도로 주문시에만 필요하며, 본체와 함께 제공되는 프로브는 공장에서 사전 보정 된 상태로 공급됩니다.
Adhesive rings
surface blood flow probe를 피부에 고정하는 데 사용되는 양면 접착 링입니다. 200 개로 판매됩니다.
Miniature needle probe holders
MNP100NX-3 / 10 needle probe와 함께 사용하기 위한 소형 홀더입니다. 5mm 또는 10mm 직경으로 제공되며 5 개 팩으로 판매됩니다.
Journal Citations
A comprehensive record of journal articles citing our blood flow monitors (172kb)
Articles of note
Daneva Z, Dempsey SK, Ahmad A, Li N, Li P-1L and Ritter JK (2019). Diuretic, natriuretic, and vasodepressor activity of a lipid fraction enhanced in the medium of cultured mouse medullary interstitial cells by a selective FAAH inhibitor. JPET Fast Forward DOI: 10.1124/jpet.118.252320.
Ganesh T, Zakher , Estrada M and Cheng HM (2019). Assessment of microvascular dysfunction in acute limb ischemia-reperfusion injury. J Magn Reson Imaging 49(4), 1174-118.
McBride DW Reis C, Zhang JH, Applegate R 2nd and Tang J (2018). Remote Limb Ischemic Preconditioning Attenuates Cerebrovascular Depression During Sinusoidal Galvanic Vestibular Stimulation via α1-Adrenoceptor-Protein Kinase Cε-Endothelial NO Synthase Pathway in Rats. J Am Heart Assoc:7(7). PII: e007105.
주문정보
| 제품번호 | 품명 | 규격 | 제조사 | 비고 |
| OXYFLO | OXYFLO 1 Channel microvascular blood flow monitor |
set | Oxford Optronix | Body only |
| OXYFLO PRO | OXYFLO PRO 2 Channel microvascular blood flow monitor |
set | Oxford Optronix | Body only |
| OXYFLO PRO XL | OXYFLO PRO XL 4 Channel microvascular blood flow monitor |
set | Oxford Optronix | Body only |
| Blood Flow (LDF) Probes (for OxyFlo and OxyFlo Pro monitors; 3 m length unless stated) | ||||
| MSP100NX | Standard surface blood flow probe (17 mm diam.) | ea | Oxford Optronix | |
| MSP110NX | Digit surface blood flow probe (17 mm diam.) | ea | Oxford Optronix | |
| MSP300NX | Miniature surface blood flow probe (suturable, 12 mm diam.) | ea | Oxford Optronix | |
| MSP310NX | Miniature surface blood flow probe (non-suturable, 12 mm diam.) | ea | Oxford Optronix | |
| MNP100NX | Standard needle blood flow probe (30 mm needle, 1 mm diam.) | ea | Oxford Optronix | |
| MNP100NX-3/10 | Needle blood flow probe for MCAO (10 mm needle, 1 mm diam.) | ea | Oxford Optronix | |
| MNP110NX | Fine needle blood flow probe (30 mm needle, 0.5 mm diam.) | ea | Oxford Optronix | |
| MNP150NX | Bent tip blood flow needle probe (30 mm needle, 1 mm diam.) | ea | Oxford Optronix | |
| Accessories | ||||
| CAL KIT | Calibration kit for LDF probes and MSFD NX adapter | set | Oxford Optronix | |
| MSP140AR | Double-sided adhesive rings for surface LDF probes. Pack of 200 | pack | Oxford Optronix | |
| MH-05 | Miniature holders for MNP100XP probe (5 mm diam.). Pack of 5 | pack | Oxford Optronix | |
| MH-10 | Miniature holders for MNP100XP probe (10 mm diam.). Pack of 5 | pack | Oxford Optronix | |
| LabChart® Pro | LabChart® Pro acquisition software (PC/Windows® only), incl. 1 user license, 5 years free updates, USB cable(s) |
software | ADInstruments | |
| POWERLAB 4/26 | 4 Channel data recorder (PC/Mac), incl. LabChart® software, 5 years free updates |
unit | ADInstruments | |
| POWERLAB 8/35 | 8 Channel data recorder (PC/Mac), incl. LabChart® software, 5 years free updates |
unit | ADInstruments | |
| POWERLAB 16/35 | 16 Channel data recorder (PC/Mac), incl. LabChart® software, 5 years free updates |
unit | ADInstruments | |
Document
| 제품자료 | OxyFlo-flyer-v2023a.pdf | Upload date: 2023.01.06 |
| 제품 매뉴얼 | OxyFlo User Manual v1.1.pdf | Upload date: 2023.01.06 |
| 제품 매뉴얼 | OxyFlo Pro User Manual v1.1.pdf | Upload date: 2023.01.06 |