Project Description

OxyLite & OxyLitePro

제품 소개

OxyLite는 조직 내 pO2와 산소분압 정보를 저산소 상태에서도 민감하고 정확하게 측정하는 산소분압측정기입니다.
calibration, sensor drift, 전용 PC나 소프트웨어가 필요 없어, 사용이 가장 간단한 dissolved oxygen monitor 장비입니다.
형광 기반의 기술을 이용한 oxygen monitoring을 통해 mmHg or kPa 당 용존산소량을 정확하게 측정할 수 있습니다.
생체 내에서는, 혈액의 헤모글로빈 산소 상태를 나타내는 oxygen saturation assessment (pulse oximetry)와 달리 세포 및 조직에 산소 가용성을 직접 판독할 수 있습니다.
3세대 opto-electronics를 사용하여 저산소 상태(0~15 mmHg)에서 pO2 range 정보를 민감하고 정확하게 제공합니다.

Applications

• Physiology/Ischaemia
• Methodology/Validation
• Tumour/Cancer
• In Vitro Applications
• Ophthalmology
• Plastic Surgery/Wound Healing
• Vital Organs/Shock
• Cerebral/Stroke/MCAO

제품 특징

• 측정 시점에서 산소의 소비가 0이기 때문에 극도의 저 산소 상태에서도 지속적이고 절대적인 산소 감지에 적합합니다.
• EEPROM 기술이 내장되어 있어 모든 보정 절차를 생략하여 탁월한 사용 편의성을 제공합니다.
• In vivo pO2 측정과 in vitro(hypoxic cell culture, tissue constructs)의 용존 산소량 측정 모두 완벽하게 지원합니다.
• 산소 센서의 직경은 대략 230 – 750µm 로 tissue monitoring에 적합하며, 사용시 조직 손상을 최소화합니다

Single-channel monitor
– Oxygen (pO2) & temperature monitor
– In vivo & in vitro applications
– No calibration procedures

Multi-channel monitor
– Oxygen (pO2) & temperature monitor
– In vivo & in vitro applications
– No calibration procedures

Data Examples
A model of muscle fatigue in mouse. 이 값은 mmHg/ degrees C 로 보여집니다.

Supplied in sealed Tyvek® pouches
재사용 가능한 다양한 종류의 oxygen sensors는 안전한 보관을 위해 전용 파우치에 제공됩니다.

제품사양

GENERAL
 Dimensions OxyLite:              95mm (H) x 290mm (W) x 260mm (D)
OxyLite Pro:      150mm (H) x 310mm (W) x 280mm (D)
 Weight OxyLite:             2kg / 4.5lbs
OxyLite Pro:      4kg / 9lbs
 Operating temperature 10 – 30°C
 Operating humidity 0 – 70% (non-condensing)
 Power requirements OxyLite:             VAC 100-240V, 50-60Hz, 30W max
OxyLite Pro:      External PSU (100-240V / 47-63 Hz), 40W max
 Fuse rating OxyLite:             2 x T1.6A
OxyLite Pro:      Not applicable
 Number of sensors supported /
Number of channels
OxyLite:                  1
OxyLite Pro:          2
OxyLite Pro XL:   4
 Display OxyLite:              40 character alphanumeric OLED
OxyLite Pro:      High contrast 800 x 480 LCD touch-screen
 Instrument configuration OxyLite:             Via function button at rear
OxyLite Pro:      Via touch-screen display
 Analogue voltage outputs OxyLite:                2 x male BNC connectors (2 outputs)
OxyLite Pro:         1 x 15-pin D-type (4 outputs)
OxyLite Pro XL:  2 x 15-pin D-type (8 outputs)
 LED excitation wavelength 525nm
 Luminescence wavelength 650nm
 Digital output USB type B interface for data recording to LabChart software (PC only)
 Analogue output OxyLite:         2 x BNC connectors for data recording (0-5V)
OxyLite Pro:    15-pin D-connector interface for data recording via BNC adapter cable (0-5V)
 PERFORMANCE
 Mode of operation Luminescence decay lifetime (pO2) / T-type thermocouple or manual user input (temperature)
 Measurement units (displayed) mmHg or kPa / ºC
 Measurement range 0~200mmHg; 0~26.6kPa / 0~50ºC
 Measurement resolution 0.1mmHg / 0.1ºC
 Measurement accuracy Oxygen:
±0.7mmHg (0~7mmHg)
±10% of reading (7~150mmHg)
±15% of reading (150~200mmHg)Temp: ±0.2ºC
 Measurement response time < 20s (standard oxygen sensor) / < 2s (temperature)
 Measurement sampling rate 1Hz (user definable on OxyLite Pro models)
 Measurement acquisition time 1s
 Measurement averaging 5s, rolling
 Display update interval (numerical) 2s (5s rolling averaged)
 Validated temp compensation range 10ºC~45ºC
 Sensor identification Automatic; integrated connector EEPROM
 Sensor calibration Factory pre-calibration (unique per sensor); valid 6 months
 Sensor shelf-life 2 years from factory calibration (used or unused)
 Sensor longevity 48 hours accumulated usage at default sampling rate
 Analogue data output range 0~5V (0~200mmHg / 0~50ºC) (default)
 Analogue data output rate 1Hz

주문정보

제품번호 품명 규격 제조사 비고
OXYLITE OXYLITE
1 Channel tissue pO2 and temperature monitor
set Oxford Optronix Body only
OXYLITE PRO OXYLITE PRO
2 Channel tissue pO2 and temperature monitor with touch screen
set Body only
OXYLITE PRO XL OXYLITE PRO XL
4 Channel tissue pO2 and temperature monitor with touch screen
set Body only
Oxygen Sensors, 최소 주문량-2개
NX-BF/O/E pO2 ‘Bare-Fibre’ sensor ea Oxford Optronix
NX-BF/OT/E pO2/Temp ‘Bare-Fibre’ sensor ea
NX-BF/OF/E pO2/Flow ‘Bare-Fibre’ sensor ea
NX-BF/OFT/E pO2/Flow/Temp ‘Bare-Fibre’ sensor ea
NX-NP/O/E pO2 Needle sensor (23G) ea
NX-LAS-1/O/E pO2 Large Area Sensor (3 m length; 1 mm2 sampling area) ea
NX-LAS-1/OT/E pO2/Temp Large Area Sensor (3 m length; 1 mm2 sampling area) ea
NX-LAS-8/O/E pO2 Large Area Sensor (3 m length; 8 mm2 sampling area) ea
NX-LAS-8/OT/E pO2/Temp Large Area Sensor (3 m length; 8 mm2 sampling area) ea
ST-NX-LAS-1/O/E pO2 ‘Large Area’ sensor, sterile (5 m length; 1 mm2 sampling area) ea
NX-MRI/BF/O/E pO2 Bare-Fibre sensor for MRI (8 m length) ea
NX-MRI/BF/OF/E pO2/Flow Bare-Fibre sensor for MRI (8 m length) ea
Accessories
LabChart® Pro LabChart® Pro acquisition software (PC/Windows® only),
incl. 1 user license, 5 years free updates, USB cable(s)
software Oxford Optronix
NX-CI ADAPTER Connecting adapter for implantable pO2 sensors (2.5 m) ea

Oxygen sensors for OxyLite™ and OxyLite™ Pro

Bare-Fibre Oxygen Sensors

NX-BF/O/E – Oxygen-only bare-fibre sensor
Suitable for localized oxygen measurements from virtually any tissue type, or for in vitro dissolved oxygen applications.
NX-BF/OT/E – Oxygen/Temperature bare-fibre sensor
Suitable for localized combined oxygen/temperature measurements from virtually any tissue type, or for in vitro dissolved oxygen applications.


Needle Oxygen Sensors

NX-NP/O/E – Oxygen-only needle-encased sensor
Suitable for localized oxygen measurements from virtually any tissue type, or for in vitro dissolved oxygen applications.


Large Area Oxygen Sensors

NX-LAS-1/O/E – Oxygen-only large area sensor (1 mm²)
Suitable for localized oxygen measurements from virtually any tissue type, or for in vitro dissolved oxygen applications.
NX-LAS-8/O/E – Oxygen-only large area sensor (8 mm²)
Suitable for very large tissue sampling area/volume (8 mm²) for area-averaged tissue oxygen measurements.
NX-LAS-8/OT/E – Oxygen/Temperature large area sensor (8 mm²)
Suitable for very large tissue sampling area/volume (8 mm²) for area-averaged tissue oxygen/temperature measurements.


Implantable oxygen sensor

NX-CI/BF/O/E – Implantable bare-fibre type oxygen sensor
Suitable for chronic tissue implantation.
NX-CI/LAS-1/O/E – Implantable large area type oxygen sensor (1 mm²)
Suitable for 1 mm² tissue sampling area/volume.
NX-CI/LAS-8/O/E – Implantable large area type oxygen sensor (8 mm²)
Suitable for very large tissue sampling area/volume (8 mm²) for area-averaged tissue oxygen measurements.

악세서리

LabChart® Pro
옵션 소프트웨어인 LabChart® Pro를 사용하면 본체의 후면에 있는 전용 USB 출력을 통해 실시간 측정치를 PC로 direct streaming 가능합니다.

NX-CI ADAPTER
Our specialist implantable (‘CI’ type) oxygen sensors require this 2.5 m connecting adapter.

Articles

In vivo tissue oxygenation: How do I know which method is best for my research?
by Sarah McFarlane, 18 October 2019

Understanding oxygen sensing in cells: A video lecture by Dr. Peter Ratcliffe.
by Justin Croft, 27 August 2019

Investigating mechanisms driving acute kidney injury arising from heart surgery and sepsis.
by Sarah McFarlane, 12 July 2019

Marina N et al. (2020). Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow.
Nat Commun 11(1), 131

Sheng T, Ong YH, Guo W and Zhu T (2020). Reactive oxygen species explicit dosimetry to predict tumor growth for benzoporphyrin derivative-mediated vascular photodynamic therapy.
J Biomed Opt. 25(6), 1-13

Gehrung M, Bohndiek SE and Brunker J (2019). Development of a blood oxygenation phantom for photoacoustic tomography combined with online pO2 detection and flow spectrometry.
J Biomed Opt. 24(12), 1-11

Tran CHT, George AG, Teskey GC and Gordon GR (2019). Seizures cause sustained microvascular constriction associated with astrocytic and vascular smooth muscle Ca2+ recruitment.
bioRxiv http://dx.doi.org/10.1101/644039

Baark F, Shaughnessy F, Pell VR, Clark JE, Eykyn TR, Blower P and Southworth R (2019). Tissue acidosis does not mediate the hypoxia selectivity of [64Cu][Cu(ATSM)] in the isolated perfused rat heart.
Sci Rep 9(1), 499

Bodo S, et al. (2019). Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury.
J Clin Invest. 129(2), 786-801

Document

제품 자료 OxyLite flyer 2017.pdf Download Size : 1.26Mb
제품 매뉴얼 OxyLite User Manual.pdf Download Size : 2.02Mb
제품 매뉴얼 OxyLite Pro User Manual.pdf Download Size : 4.00Mb