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Molnova Natural Compounds

제품 소개

Molnova는 화학 및 생물학 연구 제품 및 서비스를 전문으로 하는 글로벌 생명 공학 기업입니다.
20개 이상의 signaling pathways와 400여개의 표적에서 9,000개 이상의 제품을 제공하는 글로벌 화합물 및 펩타이드 공급업체 중 하나 입니다.
Molnova는 암, 감염, 면역학, 신경과학, 세포 사멸 및 대사 장애 등과 같은 다양한 연구 분야에 걸쳐 광범위한 제품 라인을 보유하고 있습니다.

Molnova는 새로운 생명 과학 시약, inhibitors, peptides, activator, API 및 과학적 용도의 natural compound를 포함하여 광범위한 고품질의 연구용 chemical compound를 제공합니다.
또한 chemical synthesis, peptide synthesis, drug screening 등의 최신 맞춤형 서비스를 제공합니다.
Molnova는 pre-clinical drug의 연구를 위한 신규 표적 및 신규 후보 화합물에 중점을 두고 있으며, 매년 1,000개 이상의 신제품을 출시하고 있습니다.

Hot Targets

Akt Aurora Bcl-2 Bcr-Abl
c-Myc COX DAG DPP-4
HDAC Hedgehog HER2 HIF
JAK JNK LTR MAPK
p38 MAPK p53 PARP PD-1/PD-L1
PKA PKC PLK PTEN
Src STAT TGF-beta Smad
BTK CaMK cAMP c-Met
EGFR ERK FLT3 GSK-3
HSP IAP IGFR IL Receptor
MEK mTOR NF-κB OX Receptor
PDGFR PDK PERK PI3K
Raf Rho ROCK ROS
TNF-alpha Tyrosinase VEGFR More…

 

Research Areas

Cancer

Blood cancer(217) Bone Cancer(12) Brain Cancer(27) Breast Cancer(73)
Chemotherapeutic(44) Colon Cancer(21) Gastric Cancer(17) Kidney Cancer(15)
Liver Cancer(24) Lung Cancer(77) Ovarian Cancer(27) Pancreatic Cancer(18)
Prostate Cancer(21) Skin Cancer(17) Solid Tumors(77) Thyroid Cancer(1)


Cardiovascular Disease

Dyslipidemia(25) Atherosclerosis(10) Coagulation Disorder(1) Heart Arrhythmia(25)
Hypercholesterolemia(9) Hypertension(56) Ischemia(5) Thrombosis(38)


Inflammation/Immunology

Rheumatoid Arthritis(53) Allergy(17) Asthma(47) COPD(34)
Dermatitis(6) Gout(1) Multiple Sclerosis(21) Psoriasis(22)


Infection

Rhinovirus Infection(3) Bacterial Infection(51) CMV Infection(4) Ebola Virus Infection(3)
Fungal Infection(14) HBV Infection(7) HCV Infection(48) HIV Infection(52)
HPV Infection(2) HSV Infection(8) Influenza(10) Parasite Infection(21)

Products

Wnt/Notch/Hedgehog

 Autotaxin  Axin  Beta-catenin
 γ-secretase  Dishevelled  Dkk-1
 Frizzled  Gli  Hippo
 Notch  Porcupine  Smoothened (Smo)
 STAT  TNIK  Wnt/beta/catenin


Tyrosine Kinase

 FLT3  Ack1 (TNK2)  Angiopoietin Receptor
 Bcr-Abl  BMX Kinase  Breast Tumor Kinase
 BTK  c-Fes Kinase  c-RET
 CSF1R  DDR  Ephrin Receptor
 FAK  Insulin Receptor\  Src
 TAM Receptor  Tie-2  Trk Receptor


TGF-beta/Smad 

 TGFBR


 
Proteasome/Ubiquitin

Proteasome  Caspase  Cysteine Protease
 DUB  E1  E2
 E3 Ubiquitin Ligase  Endogenous Metabolite  HSP
 NEDD8  Other Targets  p97
 Serine Protease  Tyrosinase


PROTACs

 E3 Ligase Ligand  PEGn  PROTAC


PI3K/Akt/mTOR signaling

 PDK  Akt  S6 Kinase
 GSK-3  MELK  mTOR
 PI3K  PI4K  PIKfyve


Others

  14-3-3 Protein  AAK1  Amyloids
 Antioxidant  BMI-1  ChoK
 Clathrin  DGK  Fluorescent Dye
 Glutathione Reductase  GRK (GPCRK)  mPTP
 Other Targets  PCSK9  Platelet aggregation
 PTEN  SMN2  Spliceosome
 Thrombin  TSPO  VD


Nuclear Receptor/Transcription Factor

 c-Fos/AP-1  CREB/CBP  eIF
 Foxo1  GATA Binding Protein  Keap1-Nrf2
 KLF  LXR  MLR
 PGC-1α  Progesterone Receptor  RAR/RXR
 ROR

 

NF-κB

 MALT1  TAK1  NOD
 Free radical scavengers


Neuroscience

Norepinephrine  P2 Receptor  Adiponectin Receptor
 Other Targets  Gamma-secretase  GluR
GlyT inhibitor


Natural Products

Flavonoids  Terpenoids  Phenols


Microbiology/Virology

HCV  Antibiotic ribosome  Antifection
 Antifungal Arenavirus  CMV  Enterovirus
 Filovirus  Fungal  GluCls
 HBV  HIV  HPV
 HSV  Influenza Virus  Other Targets
 Parasite  Reverse Transcriptase  Rhinovirus


Metabolic Enzyme/Protease

CYPs  11β-HSD  15-PGDH
 ACC  ACE  AChE
 Adenylate Cyclase  ALDH  Aldose Reductase
 Aminopeptidase  Transferase  BACE
 Casein Kinase  CAT  Cathepsin
 CETP  COMT  CPG2
 Decarboxylase  Dehydrogenase  DGAT
 Dopamine beta-hydroxylase  DPP  Elastase
 FAAH  TPH  Factor Xa
 Fatty Acid Synthase  Ftase  FXR
 Glucokinase  GSNOR  Guanylate Cyclase
 HMGCR  IDH  IDO
 Xanthine Oxidase (XAO)  IMPDH  LDH
 Steroid Sulfatase (STS)  Lipase  Lipid
 Lipoxygenase  MAGL  SCD
 MAO  Retinoid Receptor  MMP
 NAMPT  Neprilysin  NKCC
 Other Targets  P450  PAI-1
 Vitamin Phosphatase  Renin Phospholipase  PPAR
 Protein Phosphatase/PTP  Thioredoxin LDL


Membrane Transporter/Ion Channel

GlyT AMPK ASBT Transporter
BCRP Beta Amyloid Carbonic Anhydrase
Chloride Channel CRAC Channel CRM1
Exportin-1 FABP GAT
GLUT Glutamate Transporter HCN Channel
iGluR Monoamine Transporter Monocarboxylate Transporter
MTP nAChR NADPH
Na-K-ATPase NKCC NMDAR
OCT Other Targets P2X Receptor
P-glycoprotein Proton Pump Sodium Channel
TRP/TRPV Channel URAT1


MAPK/ERK Signaling

 MEK p38 MAPK Ras
Raf ERK JNK
MAPKAPK2 (MK2) MAP4K MNK
MLK Other Targets


JAK/STAT Signaling

 STAT Pim


Immunology/Inflammation

PGE synthase Amino Acids and Derivatives Antiviral CD110
Cell wall Complement System FLAP
Hydroxylase Interferon Receptor IRAK
IκB kinase (IKK) Lipoxygenase LTR
MyD88 NOS PD-1/PD-L1
RLR ROS Scavenger Receptor
SphK STING TLR


GPCR/G Protein

Urotensin Receptor ACAT Angiotensin Receptor
Antibacterial Bombesin Receptor Vasopressin Receptor
Bradykinin Receptor Calcium Channel cAMP Cannabinoid Receptor
CaSR CGRP Receptor Chemokine Receptor
Cholecystokinin Receptor CRF Receptor Dopamine Receptor
Endothelin Receptor FFAR Galanin Receptor GHSR
Glucagon Receptor GPCR19 GPR119
Hedgehog (Hh) Histamine Receptor Imidazoline Receptor
Leukotriene Receptor LHR LPA Receptor
Somatostatin Receptor Lysophospholipid Receptor mAChR
MCHR Melanocortin Receptor Melatonin Receptor
mGluR Motilin Receptor Neurokinin Receptor
Neuropeptide Y Receptor Neurotensin Receptor Orexin Receptor
Other Targets OXTR P2Y Receptor
PAR Platelet-activating Factor Receptor Prostaglandin Receptor
PTH Receptor S1P Receptor SGLT


Endocrinology/Hormones

GPR MRP GR
Aromatase Opioid Receptor Estrogen Receptor/ERR
CaMK Androgen Receptor (AR) RAAS THR
COX Reductase Adrenergic Receptor
5-HT Receptor ATPase Annexin A
AhR AChR


Cytoskeleton/Cell Adhesion Molecules

Akt Microtubule/Tubulin Myosin
Selectin Kinesin Dynamin
Dynein Galectin Cadherin
HSP Ezrin Arp2/3 complex
Glucokinase Arginase GST
Gap Junction Protein


Chromatin/Epigenetic

Sirtuin HMTase DNMT
Histone Demethylase HAT Epigenetic Reader Domain
Bromodomain MicroRNA CRISPR/Cas9 COX


Cell Cycle/DNA Damage

ABC AChR Antifolate
ATM/ATR Aurora Kinase CLK
c-Myc DHFR DNA Alkylator
DNA gyrase DNA Repair Protein DNA/RNA Synthesis
DNA-PK GPR HDAC
Hec1/Nek2 Integrin LIM Kinase (LIMK)
Mps1/TTK Nucleoside Antimetabolite/Analog Other Targets
PARP PLK Potassium Channel
RAD51 Rho ROCK
Telomerase Topoisomerase Wee1


Autophagy

Mitophagy Atg Autophagy
ULK LRRK2 SIK
WNK Kinase Sigma receptor Other Targets
Arginase CXCR Thrombin
CCR


Apoptosis

IAP MDM2-p53 PKA
Fas Receptor DAPK IL Receptor
Apoptosis Caspase Other Targets
Ferroptosis PKD RIP kinase
PERK Serine/threonin kinase TNF
Apaf-1 Adenosine Receptor CFTR NF-κB p53


Antibody Drug Conjugates (ADC)

ADC Cytotoxin  ADCs Linker/Click Chemistry  Drug-Linker Conjugates


Angiogenesis

ALK EGFR FAK
IGF-1R FGFR Bcr-Abl
Chk JAK Bcl-2
VDA PDGFR c-Met/HGFR
FLT VEGFR PDE
HIF/HIF Prolyl-hydroxylase CDK c-Kit
Other Targets Src PKC
Adrenergic Receptor Syk HER/HSP

Document

제품 자료 Molnova Catalog 2020-2021-min.pdf Upload date: 2022.12.08