Project Description
Molnova Natural Compounds
제품 소개
Molnova는 화학 및 생물학 연구 제품 및 서비스를 전문으로 하는 글로벌 생명 공학 기업입니다.
20개 이상의 signaling pathways와 400여개의 표적에서 9,000개 이상의 제품을 제공하는 글로벌 화합물 및 펩타이드 공급업체 중 하나 입니다.
Molnova는 암, 감염, 면역학, 신경과학, 세포 사멸 및 대사 장애 등과 같은 다양한 연구 분야에 걸쳐 광범위한 제품 라인을 보유하고 있습니다.
Molnova는 새로운 생명 과학 시약, inhibitors, peptides, activator, API 및 과학적 용도의 natural compound를 포함하여 광범위한 고품질의 연구용 chemical compound를 제공합니다.
또한 chemical synthesis, peptide synthesis, drug screening 등의 최신 맞춤형 서비스를 제공합니다.
Molnova는 pre-clinical drug의 연구를 위한 신규 표적 및 신규 후보 화합물에 중점을 두고 있으며, 매년 1,000개 이상의 신제품을 출시하고 있습니다.
Hot Targets
Akt | Aurora | Bcl-2 | Bcr-Abl |
c-Myc | COX | DAG | DPP-4 |
HDAC | Hedgehog | HER2 | HIF |
JAK | JNK | LTR | MAPK |
p38 MAPK | p53 | PARP | PD-1/PD-L1 |
PKA | PKC | PLK | PTEN |
Src | STAT | TGF-beta | Smad |
BTK | CaMK | cAMP | c-Met |
EGFR | ERK | FLT3 | GSK-3 |
HSP | IAP | IGFR | IL Receptor |
MEK | mTOR | NF-κB | OX Receptor |
PDGFR | PDK | PERK | PI3K |
Raf | Rho | ROCK | ROS |
TNF-alpha | Tyrosinase | VEGFR | More… |
Research Areas
Cancer
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Blood cancer(217) | Bone Cancer(12) | Brain Cancer(27) | Breast Cancer(73) |
Chemotherapeutic(44) | Colon Cancer(21) | Gastric Cancer(17) | Kidney Cancer(15) | |
Liver Cancer(24) | Lung Cancer(77) | Ovarian Cancer(27) | Pancreatic Cancer(18) | |
Prostate Cancer(21) | Skin Cancer(17) | Solid Tumors(77) | Thyroid Cancer(1) |
Cardiovascular Disease
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Dyslipidemia(25) | Atherosclerosis(10) | Coagulation Disorder(1) | Heart Arrhythmia(25) |
Hypercholesterolemia(9) | Hypertension(56) | Ischemia(5) | Thrombosis(38) |
Inflammation/Immunology
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Rheumatoid Arthritis(53) | Allergy(17) | Asthma(47) | COPD(34) |
Dermatitis(6) | Gout(1) | Multiple Sclerosis(21) | Psoriasis(22) |
Infection
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Rhinovirus Infection(3) | Bacterial Infection(51) | CMV Infection(4) | Ebola Virus Infection(3) |
Fungal Infection(14) | HBV Infection(7) | HCV Infection(48) | HIV Infection(52) | |
HPV Infection(2) | HSV Infection(8) | Influenza(10) | Parasite Infection(21) |
Products
Wnt/Notch/Hedgehog
Autotaxin | Axin | Beta-catenin |
γ-secretase | Dishevelled | Dkk-1 |
Frizzled | Gli | Hippo |
Notch | Porcupine | Smoothened (Smo) |
STAT | TNIK | Wnt/beta/catenin |
Tyrosine Kinase
FLT3 | Ack1 (TNK2) | Angiopoietin Receptor |
Bcr-Abl | BMX Kinase | Breast Tumor Kinase |
BTK | c-Fes Kinase | c-RET |
CSF1R | DDR | Ephrin Receptor |
FAK | Insulin Receptor\ | Src |
TAM Receptor | Tie-2 | Trk Receptor |
TGF-beta/Smad
TGFBR | – | – |
Proteasome/Ubiquitin
Proteasome | Caspase | Cysteine Protease |
DUB | E1 | E2 |
E3 Ubiquitin Ligase | Endogenous Metabolite | HSP |
NEDD8 | Other Targets | p97 |
Serine Protease | Tyrosinase |
PROTACs
E3 Ligase Ligand | PEGn | PROTAC |
PI3K/Akt/mTOR signaling
PDK | Akt | S6 Kinase |
GSK-3 | MELK | mTOR |
PI3K | PI4K | PIKfyve |
Others
14-3-3 Protein | AAK1 | Amyloids |
Antioxidant | BMI-1 | ChoK |
Clathrin | DGK | Fluorescent Dye |
Glutathione Reductase | GRK (GPCRK) | mPTP |
Other Targets | PCSK9 | Platelet aggregation |
PTEN | SMN2 | Spliceosome |
Thrombin | TSPO | VD |
Nuclear Receptor/Transcription Factor
c-Fos/AP-1 | CREB/CBP | eIF |
Foxo1 | GATA Binding Protein | Keap1-Nrf2 |
KLF | LXR | MLR |
PGC-1α | Progesterone Receptor | RAR/RXR |
ROR |
NF-κB
MALT1 | TAK1 | NOD |
Free radical scavengers |
Neuroscience
Norepinephrine | P2 Receptor | Adiponectin Receptor |
Other Targets | Gamma-secretase | GluR |
GlyT inhibitor |
Natural Products
Flavonoids | Terpenoids | Phenols |
Microbiology/Virology
HCV | Antibiotic ribosome | Antifection |
Antifungal Arenavirus | CMV | Enterovirus |
Filovirus | Fungal | GluCls |
HBV | HIV | HPV |
HSV | Influenza Virus | Other Targets |
Parasite | Reverse Transcriptase | Rhinovirus |
Metabolic Enzyme/Protease
Membrane Transporter/Ion Channel
MAPK/ERK Signaling
MEK | p38 MAPK | Ras |
Raf | ERK | JNK |
MAPKAPK2 (MK2) | MAP4K | MNK |
MLK | Other Targets |
JAK/STAT Signaling
STAT Pim | – | – |
Immunology/Inflammation
GPCR/G Protein
Endocrinology/Hormones
GPR | MRP | GR |
Aromatase | Opioid Receptor | Estrogen Receptor/ERR |
CaMK Androgen Receptor (AR) | RAAS | THR |
COX | Reductase | Adrenergic Receptor |
5-HT Receptor | ATPase | Annexin A |
AhR AChR |
Cytoskeleton/Cell Adhesion Molecules
Akt | Microtubule/Tubulin | Myosin |
Selectin | Kinesin | Dynamin |
Dynein | Galectin | Cadherin |
HSP | Ezrin | Arp2/3 complex |
Glucokinase | Arginase | GST |
Gap Junction Protein |
Chromatin/Epigenetic
Sirtuin | HMTase | DNMT |
Histone Demethylase | HAT | Epigenetic Reader Domain |
Bromodomain | MicroRNA | CRISPR/Cas9 COX |
Cell Cycle/DNA Damage
Autophagy
Mitophagy | Atg | Autophagy |
ULK | LRRK2 | SIK |
WNK Kinase | Sigma receptor | Other Targets |
Arginase | CXCR | Thrombin |
CCR |
Apoptosis
IAP | MDM2-p53 | PKA |
Fas Receptor | DAPK | IL Receptor |
Apoptosis | Caspase | Other Targets |
Ferroptosis | PKD | RIP kinase |
PERK | Serine/threonin kinase | TNF |
Apaf-1 | Adenosine Receptor | CFTR NF-κB p53 |
Antibody Drug Conjugates (ADC)
ADC Cytotoxin | ADCs Linker/Click Chemistry | Drug-Linker Conjugates |
Angiogenesis
ALK | EGFR | FAK |
IGF-1R | FGFR | Bcr-Abl |
Chk | JAK | Bcl-2 |
VDA | PDGFR | c-Met/HGFR |
FLT | VEGFR | PDE |
HIF/HIF Prolyl-hydroxylase | CDK | c-Kit |
Other Targets | Src | PKC |
Adrenergic Receptor | Syk | HER/HSP |
Document
제품 자료 | Molnova Catalog 2020-2021-min.pdf | Upload date: 2022.12.08 |