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Chicken IgY


닭에서 생성된 polyclonal antibody는 다른 포유류에서 생산된 항체에 비해 많은 이점을 가지고 있습니다.
닭은 혈청뿐 만 아니라 노른자에서도 immunoglobulin을 생성하므로 동물의 피를 보지 않고도 단순히 egg만을 수집함으로써 항체를 쉽게 얻을 수 있습니다.

Chicken produce IgY, which migrate from the hen serum to the egg yolk. Compared to mammalian IgGs, they have one extra Fc domain

Why use Chickens?

• 닭은 포유동물이 아니므로 포유동물의 항원 단백질에 대한 높은 결합력을 가진 항체를 만드는 경향이 있습니다.
• 우리가 아는 한 Polyclonal Antibody를 생산하는 가장 인도적인 방법입니다.
닭은 피를 흘릴 필요가 없으며 우리는 계란을 모으기만 하면 됩니다.
• 닭 한 마리는 토끼 양의 10~20배에 해당하는 월 최대 3g의 IgY에 달하는 엄청난 양의 항체를 생산할 수 있습니다.
또한 토끼에 비해 닭은 항체를 훨씬 빨리 생산합니다.
• Chicken IgY Fc 영역은 포유동물 IgG와 충분히 다릅니다. (1개를 더 가지고 있습니다)
• 포유류 rheumatoid factor 나 기타 자연 발생 anti-mammalian antibodies에 결합하지 않음으로써 깨끗한 background를 얻을 수 있습니다.
• Mammalian complement system을 활성화하지 않습니다.

BRAND: Nordic, Exalpha, Gallus, MUbio, Biologo, ADG, ELTI, Scicons, Bii


  ACMYC DAIgY-F IgY-1000
Product Type Primary antibodies Secondary antibodies Control antibodies
Units 0.1 mg 0.5 mg 1000 mg
Host Chicken Donkey (Chicken) Chicken
Application ELISA
Western Blotting
Flow Cytometry
Western Blotting



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2. Van Deventer JA, Wittrup KD. 2014.Yeast surface display for antibody isolation: library construction, library screening, and affinity maturation. Methods Mol Biol. 1131:151-81.

3. Wang, S., Mata-Fink J., Kriegsman B, Hanson, M, Irvien DJ, Eisen HN, Burtn DR, Wittrup, KD, Kardar M, Chakraborty, AK. 2015. Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies. Cell 160(4):785-97.

4. Heimer, BW, Tam, BE and HD Sikes. 2015. Characterization and directed evolution of a methyl-binding protein for high-sensitivity DNA methylation analysis. Protein Eng Des Sel 28:543-551.

5. de Picciotto S, Dickson PM, Traxlmayr MW, Marques BS, Socher E, Zhao S1, Cheung S, Kiefer JD, Wand AJ, Griffith LG, Imperiali B, Wittrup KD. 2016. Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions. J Mol Biol. 428(20):4228-4241.

6. Traxlmayr MW, Kiefer JD, Srinivas RR, Lobner E, Tisdale AW, Mehta NK, Yang NJ, Tidor B, Wittrup KD. 2016. Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library. J Biol Chem 291 (43): 22496-22508.

7. Kauke, MJ, MW, Traxlmayr, MW, Parker, JA, Kiefer, JD, Knihtila, R, McGee, J, Verdine, G, Mattos, C and KD Wittrup. 2017. An engineered protein antagonist of K-Ras/B-Raf interaction. Sci. Rep. 7: 5831.

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8. Lei X-H and BR Bochner, 2013. Using Phenotype MicroArrays to Determine Culture Conditions That Induce or Repress Toxin Production by Clostridium difficile and Other Microorganisms. PLoS ONE 8(2): e56545. doi:10.1371/journal.pone.0056545.

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RB500 / IK 8000

1. Young, CA, FG Silversides, SRM Jones, 2007, Chicken-derived IgY recognizes developing and mature stages of Loma salmonae (Microsporidia) in Pacific salmon, Oncorhynchus spp., Aquaculture 273 (4): 398-404.

2. Allesandro, R., A. Gallo, M. Barranca, S. Principe, S. Taverna, G. Duro, G. Cassata, M. Becchi, S. Fontana and G. DeLeo, 2009, Production of an Egg Yolk Antibody against Parietaria judaica 2 allergen. Poult Sci. 88: 1773-1778.

3. Janardhana V, Tachedjian M, Crameri G, Cowled C, Wang LF, and ML Baker. 2012. Cloning, expression and antiviral activity of IFN? from the Australian fruit bat, Pteropus alecto. Dev Comp Immunol. 36:610-8.

4. Liu, J., Kerr, P.J., Wright, J.D. and T. Strive 2012. Serological assays to discriminate rabbit haemorrhagic disease virus from Australian non-pathogenic rabbit calicivirus. Vet. Mic. 157: 345-354.

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6. Ulrichs, T. Drotleff, A.M. and W. Ternes. 2015. Determination of heat-induced changes in the protein secondary structure of reconstituted livetins (water-soluble proteins from hen’s egg yolk) by FTIR. Food Chemistry 172:909-920.


​ 제품번호 품명 규격 제조사 비고
ACMYC Chicken anti C-MYC Epitope Tag 0.1 mg Nordic-MUbio Primary Antibody
IgY-1000 Normal Chicken IgY (egg-derived) 1000 mg Nordic-MUbio Control Antibody
DAIgY-F Donkey anti Chicken IgY (H+L), conjugated with FITC 0.5 mg Nordic-MUbio Secondary Antibody
RB500 Reagent B (IgY Precipitation) (5 yolks) Reagent B (500 ml) Exalpha Biologicals Services
IK 8000 EggsPress IgY Purification Kit (80 yolks) Reagent A (2 x 3.8L) Reagent B (2 x 3.8L) Exalpha Biologicals Kits


제품 자료 ACMYC.pdf
Upload date: 2022.01.27
제품 MSDS Antibody SDS with Sodium AzideV2.pdf Upload date: 2022.01.27
제품 매뉴얼 RB500-Kit-Manual.pdf
Upload date: 2022.01.27